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Updated: Jun 7, 2025

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从HSCs分泌的KGF激活了PAK4/BMI1,通过PI3K/AKT通路促进了HCC的干细胞生长

Qinghua Li1, Qiuyang Chen2,3, Wenchao Wang1

  • 1Department of General Surgery, Yangpu Hospital, School of Medicine, Tongji University, China.

IUBMB life
|November 15, 2024
PubMed
概括

肝细胞癌 (HCC) 干和肝纤维化是由来自肝星细胞 (HSC) 的生长因子促进的. 这种相互作用涉及通过PAK4稳定BMI1,影响PI3K/AKT通路,为HCC提供新的治疗点.

关键词:
5 - - 甲的耐药性在BMI1中,BMI1是BMI1.在PI3K/AKT信号通路中.肝脏的恒星细胞.肝细胞癌是肝细胞癌.

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