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柱状鼻手术中的病理检查:评估必要性和成本效益:十年的回顾分析

İlyas Kudaş¹, Fatih Başak², Yahya K Çalışkan³

¹Department of General Surgery, University of Health Sciences, Cam Sakura Education and Research Hospital, Istanbul, Turkey.

The American surgeon

|November 15, 2024

概括

柱状鼻疾病 (PSD) 中的恶性病很少见,发生在0.13%的病例中. 高龄和更长的疾病持续时间等危险因素可以帮助针对这种罕见的癌症进行病理学检查.

科学领域:

在瘤学瘤学.
手术病理学手术病理学
皮肤病学皮肤病学

背景情况:

柱状鼻疾病 (PSD) 很少表现为恶性瘤,最常见的是状细胞癌 (SCC).
在PSD中识别恶性瘤风险因素对于优化诊断策略至关重要.

研究的目的:

为了确定患有柱状鼻疾病 (PSD) 的患者恶性瘤的发生率.
确定与PSD恶性瘤相关的重大风险因素.
为了告知有针对性的病理检查协议.

主要方法:

在2014-2023年期间,对1505名为PSD进行外科切除的患者进行了回顾性分析.
排除具有不完整基因病理学数据的患者.
对所有手术样本进行组织病理学检查,以检测恶性瘤.

主要成果:

诊断出两例 (0.13%) 状细胞癌 (SCC).
确定了恶性病变的风险因素:年龄超过40岁 (OR 3.2) 和疾病持续时间超过3年 (OR 2.8).
两位SCC患者都成功地接受了手术和辅助放射治疗,在2年的随访中仍然没有疾病.

结论:

在PSD中恶性病是罕见的事件,发病率为0.13%.
晚年和长时间的疾病持续时间是PSD恶性瘤的重要风险因素.
基于已识别的风险因素的选择性病理检查可以提高成本效益和诊断重点.

关键词:

经济效益性经济效益性恶性瘤是一种恶性瘤.病理学检查病理学检查柱状鼻腔是指柱状鼻腔.有关风险因素的风险因素.手术样本的手术样本

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