瘦肉代谢功能障碍相关的脂肪性肝病 (MASLD) 的诊断和管理:系统性审查
Basile Njei1, Prince Ameyaw2, Yazan Al-Ajlouni3
1Department of Medicine, Yale School of Medicine, New Haven, USA.
Cureus
|November 15, 2024
概括
瘦身代谢功能障碍相关的脂肪性肝病 (MASLD) 影响非肥胖个体. 本综述强调了诊断和管理精益MASLD的挑战,强调需要提高认识和个性化治疗.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢疾病 代谢疾病
- 肝脏健康 肝脏健康
背景情况:
- 瘦身代谢功能障碍相关的脂肪性肝病 (MASLD) 提出了一个诊断和管理的挑战,与与肥胖相关的脂肪性肝病不同.
- 改名为MASLD反映了对非肥胖个体脂肪肝导致的代谢因素的更广泛理解.
- 有限的认识和传统的诊断标志物阻碍了对瘦肉大的有效护理.
研究的目的:
- 系统地审查当前关于瘦肉 MASLD 的诊断和管理的文献.
- 确定在精益 MASLD 中改善临床护理的挑战和潜在解决方案.
- 突出进一步研究和提高认识的需要.
主要方法:
- 在2023年12月4日,在六个数据库中进行了系统的文献搜索.
- 包括英语同行评审的研究,重点关注精益 MASLD 诊断和管理.
- 遵循系统审查和元分析 (PRISMA) 准则的首选报告项目.
主要成果:
- 诊断精益MASLD是困难的,传统标记物的局限性和先进成像的潜力.
- 管理策略包括改变生活方式和向药理疗法.
- 大部分审查的研究集中在诊断挑战 (43) 和管理策略 (52).
结论:
- 提高临床意识,定期监测和个性化治疗方法对于精益MASLD至关重要.
- 需要进一步的研究来完善诊断标准和开发有针对性的治疗方法.
- 对于患有瘦肉肌肌痛的人来说,增强理解和护理是必不可少的.
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