在共同提取金生和史奇桑德拉蛋白质时具有协同效应
Han Zhang1, Haidong Wang1, Hongyan Zhou1
1Changchun University of Chinese Medicine, Changchun, China.
Frontiers in nutrition
|November 15, 2024
概括
从人参和石山德拉共同提取的蛋白质表现出卓越的抗氧化活性和协同效应. 这项研究揭示了因其增强性质而在功能性食品中共同提取蛋白 (COP) 的潜力.
科学领域:
- 食品科学 食品科学 食品科学
- 生物化学 生物化学
- 传统中国医药 传统中国医药
背景情况:
- 人参和草是中国传统的植物,以增强免疫力的特性而闻名.
- 它们经常在传统医学中一起使用,以增强治疗效果,创造协同效应.
- 这种协同作用背后的具体机制,特别是在蛋白质水平上,仍然不清楚.
研究的目的:
- 为了研究金生 - 石山组合对宏分子蛋白质的协同效应.
- 为了比较联合提取蛋白 (COP) 与简单混合蛋白 (SMP),人参蛋白 (PGP) 和石蛋白 (SCP) 的特性.
主要方法:
- 利用双蛋白研究方法与联合提取技术来分离蛋白质.
- 将COP,SMP,PGP和SCP的物理化学特性,功能特性和抗氧化活性进行比较.
- 评估了自由基清除能力和对HepG2细胞中氧化应激标记物的影响.
主要成果:
- 联合提取的蛋白质 (COP) 对基,DPPH和ABTS+基具有最高的自由基清除活性.
- 在HepG2细胞中,COP显著降低了活性氧物种 (ROS) 和甲 (MDA) 水平.
- COP增加了抗氧化酶的细胞内水平,包括超氧化脱氧化酶 (SOD),谷氨过氧化酶 (GSH-Px),催化酶 (CAT) 和乳酸脱酶 (LDH).
结论:
- 联合提取的蛋白质 (COP) 有助于在人参-奇桑德拉组合中观察到的协同效应.
- 联合提取在蛋白质生产中提供了优势,产生了增强的功能和抗氧化特性.
- COP显示了在功能性食品行业的应用潜力.
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