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嗅觉上皮质感染的SARS-CoV-2:可能的神经炎症后果的COVID-19

Ana G Gutiérrez-García¹, Carlos M Contreras²

¹Laboratorio de Neurofarmacología, Instituto de Neuroetología, Universidad Veracruzana, Xalapa, Mexico.

Complex psychiatry

|November 15, 2024

概括

由于COVID-19 (冠状病毒疾病2019) 的嗅觉丧失,可能导致情绪障碍. 这种嗅觉功能障碍会影响情绪和生活质量,这是由于潜在的神经炎症和中枢神经系统的影响.

科学领域:

神经科学是一个神经科学.
传染性疾病传染性疾病
耳鼻喉科耳鼻喉科耳鼻喉科

背景情况:

嗅觉丧失是COVID-19的一个关键症状,涉及到定量 (厌氧,低氧) 或定性 (异氧) 变化.
鼻上皮质结构的损伤是这些嗅觉变化的基础.
嗅觉系统与处理情绪的大脑区域的直接神经连接表明与情绪障碍有联系.

研究的目的:

探索COVID-19相关的嗅觉功能障碍和情绪障碍之间的联系.
研究神经炎症在COVID-19后情绪症状中的潜在作用.
了解嗅觉系统损伤如何影响患者的生活质量.

主要方法:

关于COVID-19,嗅觉功能障碍和神经/情绪影响的科学文献的综述.
分析嗅觉系统与涉及情绪的大脑中心之间的解剖和功能联系.
嗅觉上皮损伤与神经炎症过程和心理痛苦的相关性.

主要成果:

COVID-19 嗅觉功能障碍可能导致情绪和生活质量出现重大障碍.
神经炎症过程可能会调解嗅觉丧失和情绪障碍之间的联系.
COVID-19患者的嗅觉功能障碍与焦虑,抑郁和自我感知的生活质量降低并发.

结论:

由于COVID-19引起的嗅觉功能障碍可能会通过神经炎症和中枢神经系统参与导致情绪障碍.
病毒通过嗅球影响中枢神经系统的潜力突显了COVID-19后情绪症状中的神经因素.
解决嗅觉功能障碍对于管理COVID-19患者的整体健康和生活质量至关重要.

关键词:

焦虑焦虑是一种焦虑.在 COVID-19 疫情中,抑郁症抑郁症抑郁症情绪情绪情绪嗅觉功能障碍嗅觉功能障碍生活质量生活的质量.

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