HMicroDB:一个综合的赫尔培动物微生物群数据库,专注于宿主细胞系,生理特征和环境因素
Jiaying Li1, Yuze Gao2, Guocheng Shu3
1Department of Automation, Tsinghua University, Beijing, China.
Molecular ecology resources
|November 15, 2024
概括
研究人员创建了Hermetofaunal微生物群数据库 (HMicroDB),以探索两动物,爬行动物及其微生物之间的联系. 该数据库有助于理解宿主微生物群的共同进化和保护工作.
科学领域:
- 微生物学 微生物学
- 类学 类学 类学 类学
- 生物信息学是一种生物信息学.
背景情况:
- 共生微生物群在各种动物种群中显著影响宿主生理学.
- 两动物和爬行动物 (herpetofauna) 在生态和进化上具有重要意义,它们的相关微生物群受到宿主基因,特征和环境的影响.
- 现有的关于动物微生物群的数据是分散的,这限制了全面的分析和资源的可访问性.
研究的目的:
- 开发第一个对菌动物微生物群的综合数据库.
- 为研究两动物和爬行动物的宿主微生物相互作用的研究人员提供一个集中,可搜索的资源.
- 促进对类动物,它们的共生微生物群和环境因素之间的关系的探索.
主要方法:
- 构建带动物微生物群数据库 (HMicroDB),整合来自337种宿主物种的11,697个微生物样本.
- 在23个体位点对11,084种微生物种群进行了标准化的注释和分析.
- 包括23个宿主表型或环境因素进行综合分析.
主要成果:
- HMicroDB提供了对菌动物微生物群的全面数据集,涵盖了许多物种,身体部位和相关因素.
- 一致的注释和标准化分析确保了数据的可靠性和可比性.
- 数据库具有用户友好的界面,具有交互式可视化,用于数据探索.
结论:
- HMicroDB 是一个有价值的资源,用于调查宿主-微生物群共进化在herpetofauna.
- 该数据库通过提供有关微生物社区动态的见解,支持生物保护研究.
- 促进对资源利用和其他涉及动物微生物群的生态相互作用的探索.
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