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Updated: Jun 9, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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发现了第一类双TSPO/碳酸无水酶调节剂,具有有前途的神经营养活动

Valeria Poggetti1, Elisa Angeloni1, Lorenzo Germelli1

  • 1Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.

ACS chemical neuroscience
|November 15, 2024
PubMed
概括

研究人员开发了针对神经退行性疾病的18kDa转位蛋白 (TSPO) 和碳酸酶 (CA) 的新型双调节器. 衍生品3通过刺激TSPO,激活CA VII和调高来自大脑的神经营养因子,显示出有前途的结果.

关键词:
2 - 英二烯的使用方法碳酸无水酸是碳酸无水的一种.多个目标导向的带.神经退行性疾病的神经退行性疾病神经保护神经保护转位蛋白是一种转位蛋白.

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