修改教科书结果是口腔癌手术后早期死亡率的预测因素
Ling-Jan Chiou1, Ching-Chih Lee2,3,4,5,6
1Department of Healthcare Administration, Asia University, Taichung, Taiwan, R.O.C.
Annals of surgical oncology
|November 15, 2024
概括
口腔癌 (OCC) 患者的早期死亡是由非修改的教科书结果 (mTO) 和癌症资源中心 (CRC) 访问以及传统因素预测的. 一种新型的诺姆图谱有助于预测存活率,从而改善患者的治疗结果.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 癌症预后 癌症预后
背景情况:
- 口腔癌 (OCC) 对患者的生存构成重大挑战.
- 在OCC手术后的早期死亡率需要确定关键的预后因素.
研究的目的:
- 确定口腔癌 (OCC) 患者早期死亡的预后因素.
- 制定改善OCC手术后患者治疗结果的策略.
主要方法:
- 对397名接受初级瘤切除和部剖析的患者 (2017-2021) 的回顾性分析.
- 单变量和多变量考克斯回归分析,以确定早期死亡 (12个月内) 的预测因素.
- 开发一种名谱来估计1年整体存活率 (OS).
主要成果:
- 整体早期死亡率为12.6%.
- 早期死亡率的独立预测因素包括未经修改的教科书结局 (mTO),晚期结节阶段 (pN2-3),较大的瘤大小 (>3厘米) 和淋巴血管入侵.
- 纳入这些因素的名图显示出良好的预测性能.
结论:
- 除了临床病理特征外,非mTO和癌症资源中心 (CRC) 访问也是OCC早期死亡的重要预后因素.
- 一个经过验证的nomogram可以帮助预测生存率.
- 改善mTO和患者获得资源的机会可能会提高OCC的生存结果.
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