肠内的生理学 肠内的生理学
Jacques Gonzales1, Brian D Gulbransen1
1Department of Physiology, Michigan State University, East Lansing, Michigan, USA;
Annual review of physiology
|November 15, 2024
概括
肠道质细胞是肠道神经系统的关键合作伙伴,维持肠道平衡. 它们的功能在疾病中发生变化,导致炎症,运动问题和疼痛.
科学领域:
- 神经科学是一个神经科学.
- 胃肠病学 胃肠病学
- 细胞生物学 细胞生物学
背景情况:
- 肠膜是胃肠道中肠道神经系统 (ENS) 的组成部分.
- 这些质细胞与神经元,免疫细胞和肠表皮相互作用,以维持肠道平衡.
研究的目的:
- 审查肠道细胞的多样化的生理作用.
- 探索肠道质对胃肠道健康和疾病病理生理学的贡献.
主要方法:
- 这是一篇综述性文章,综合了当前的研究和概念.
- 专注于有关肠道质细胞功能的最新证据.
主要成果:
- 肠道质细胞调节ENS的微环境,神经元活动,上皮功能和免疫反应.
- 质细胞影响关键的生理过程,如肠道运动性和上皮屏障完整性.
结论:
- 在疾病状态下改变的肠质表型有助于肠道炎症,动力障碍,疼痛,神经可塑性和瘤发生.
- 肠道质在维持胃肠道健康和推动肠道病理生理学方面都发挥着重要作用.
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