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Updated: Jun 7, 2025

Murine Model of CD40-activation of B cells
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Published on: March 5, 2010

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机械传导控制了CD40的功能,是X链超IgM综合征的基础

Hyun-Kyu Choi1,2,3, Stefano Travaglino1,2, Matthias Münchhalfen4

  • 1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.

Science advances
|November 15, 2024
PubMed
概括

T细胞和B细胞使用CD40-CD40L相互作用来成熟. 这些结合物的机械力增强了CD40信号传递,这对于抗体类切换至关重要,而其缺失导致X链接的超IgM综合征.

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