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蒙特卡洛建模和GammaMed Plus的剂量测定验证192Ir源用于使用TOPAS的HDR支臂疗法应用

Ravindra Shende¹, S J Dhoble², Umesh Gayake³

¹Department of Radiation Oncology, Balco Medical Centre, Naya Raipur, Sector 36, Chhattisgarh, 493661, India; Department of Physics R.T.M. Nagpur University, Nagpur, Maharashtra, 440033, India.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

|November 15, 2024

概括

进行了GammaMed Plus 192Ir支臂治疗源的蒙特卡洛 (MC) 建模和剂量计验证. 经过验证的MC模拟数据可以增强支臂治疗剂量计算和针对患者的治疗规划.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
计算科学计算科学

背景情况:

高剂量速率支臂疗法对于癌症治疗至关重要.
准确的剂量测量对于有效的支臂疗法至关重要.
蒙特卡洛 (MC) 模拟为精确的剂量计算提供了强大的工具.

研究的目的:

对GammaMed Plus 192Ir源进行MC建模和剂量计验证.
为了调查TG-43剂量计参数用于支臂治疗剂量计算.
为治疗计划系统 (TPS) 验证建立可靠的MC数据集.

主要方法:

在TOPAS MC模拟工具包中使用Geant4代码.
模拟了GammaMed Plus 192Ir手臂疗法源. 这是GammaMed Plus 192Ir手臂疗法源的模型.
根据TG-43协议指导计算和验证的关键剂量计参数.

主要成果:

在模拟和公布的剂量计数据之间取得了很好的一致性.
该MC模型准确地表示了GammaMed Plus 192Ir源特性.
验证的MC数据集为剂量计算提供了可靠的参考.

结论:

开发的MC模型和验证的剂量测量数据适合于手臂治疗应用.
模拟数据集可以集成到TPS中用于剂量计算验证.
这种MC建模方法支持未来针对患者的支臂治疗研究.

关键词:

(192) 伊朗的来源支臂疗法是一种手臂疗法.这是一个MC模拟.托帕斯 (TOPAS) 是一个著名的品牌.

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