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Updated: Jun 7, 2025

Author Spotlight: Fluorescence-Based Quantification of Mitochondrial Membrane Potential and Superoxide Levels Using Live Imaging in HeLa Cells
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Author Spotlight: Fluorescence-Based Quantification of Mitochondrial Membrane Potential and Superoxide Levels Using Live Imaging in HeLa Cells

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通过ATF5介导的线粒体展开蛋白质反应可以保护SH-SY5Y细胞的Pb诱导的线粒体损伤

Yihan Xu1, Min Liu2, Sikang Gao3

  • 1Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.

Neurotoxicology
|November 15, 2024
PubMed
概括

线粒体未折叠蛋白反应 (mtUPR) 保护神经细胞免受毒性影响. 通过ATF5激活mtUPR可以保护线粒体,减少氧化应激和暴露引起的细胞死亡.

关键词:
在ATF5中使用ATF5.领导 领导 领导 领导 领导线粒体展开的蛋白质反应反应神经毒性 神经毒性

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