肺栓塞和恶性瘤患者的基线特征,治疗模式和结果:来自单中心研究的见解
Aykun Hakgor1, Barkın Kultursay2, Berhan Keskin3
1Istanbul Medipol University, Medipol Mega University Hospital, Dept. of Cardiology, Istanbul, Turkey.
International journal of cardiology
|November 15, 2024
概括
活跃癌症显著恶化了急性肺栓塞 (PE) 患者的结果. 尽管死亡风险较高,但导管治疗为这些易受伤害的个体提供了有效的解决方案,可接受的出血率.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 肺部医学 肺部医学
背景情况:
- 急性肺栓塞 (PE) 是癌症患者死亡的主要原因.
- 恶性病症显著影响急性PE的治疗决策和临床结果.
研究的目的:
- 评估活跃恶性瘤对急性PE治疗选择的影响.
- 评估急性PE患者的短期和长期临床结果,包括患有或没有活跃癌症的急性PE患者.
主要方法:
- 对872名急性PE患者的回顾性分析.
- 患者被分为两组:活跃的恶性瘤和没有活跃的恶性瘤.
- 在不同组之间比较治疗方法和临床结果.
主要成果:
- 在14.8%的患者中存在活跃恶性瘤.
- 溶解性血栓切除和抗凝药在恶性瘤患者中更为常见.
- 在恶性瘤队列中观察到更高的住院和长期死亡率.
- 活跃恶性瘤独立预测了不良结果,包括死亡率和再住院.
结论:
- 同时的恶性瘤会对急性PE患者的短期和长期结果产生不利影响.
- 基于导管的干预可以在可接受的出血率下取得令人满意的治疗成功.
- 患有恶性瘤和急性PE的患者由于脆弱性增加,需要谨慎管理.
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