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POGK是一种化KRAB域含有可转移的元素,在乳腺癌中具有瘤抑制功能

Karen M Mann1

  • 1Department of Molecular Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.

Trends in cell biology
|November 15, 2024
PubMed
概括

可转移元素 (TE) 是重要的基因促进体. 一种特定的TE,POGK,通过与TRIM28合作来抑制三阴性乳腺癌 (TNBC) 中的核糖体基因转录,表现出瘤抑制活性.

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