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Updated: Jun 7, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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Published on: March 6, 2018

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科利巴克对前列腺癌产生了依赖于雄激素和独立于雄激素的作用

Raag Agrawal1, Sarah Al-Hiyari2, Rupert Hugh-White2

  • 1Department of Human Genetics, University of California-Los Angeles, Los Angeles, CA, USA; Department of Urology, University of California-Los Angeles, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Center, University of California-Los Angeles, Los Angeles, CA, USA.

European urology oncology
|November 15, 2024
PubMed
概括

生产可利巴克的大肠杆菌通过诱导基因组不稳定性,可能导致前列腺癌 (PC). 这种细菌毒素与像DHT这样的雄激素相结合,在PC细胞中协同增加体质突变和kataegis.

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