在需要降脂治疗的心血管疾病患者中,通过最佳的药物坚持预计节省成本:一项跨国经济评估研究
Jeong-Yeon Cho1, Fernando A Wilson2, Usa Chaikledkaew3
1Department of Pharmacotherapy College of Pharmacy, University of Utah Salt Lake City UT USA.
Journal of the American Heart Association
|November 15, 2024
概括
改善对心血管疾病治疗的坚持可以预防事件并节省成本. 墨西哥,泰国和中国的最佳遵守为需要二次预防的患者提供了显著的健康和经济效益.
科学领域:
- 卫生经济学 卫生经济学
- 心血管医学 心血管医学
- 公共卫生政策 公共卫生政策
背景情况:
- 对慢性心血管治疗的不良坚持会对临床结果产生负面影响.
- 这项研究侧重于墨西哥,泰国和中国需要二次预防的心血管疾病患者.
研究的目的:
- 估计改善心血管疾病患者治疗坚持的好处.
- 从患者和社会的角度分析对临床结果和医疗保健成本的影响.
主要方法:
- 马尔科夫模型对一个生命周期的模拟.
- 优化遵守的比较 (基于51个RCT的元分析) 与现状.
- 利用对4,051,338名患者的剂量反应元分析,将坚持与结果联系起来.
主要成果:
- 最佳的坚持可以防止42-63个心血管事件每1000名患者在三个国家.
- 观察到寿命年数和质量调整寿命年数的显著改善.
- 社会成本节约在每名患者的316美元至700美元之间,敏感性分析的结果强大.
结论:
- 为心血管疾病患者实现最佳的降脂治疗,节省成本并改善健康结果.
- 墨西哥,泰国和中国的国家医疗保健系统应实施提高患者执法率的策略.
- 改善的坚持代表了这些地区心血管疾病管理的有价值投资.
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