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Updated: Jun 7, 2025

Screening Traditional Chinese Medicine Compounds for Inhibiting UCHL3 Activity Based on Molecular Docking and Deubiquitinating Enzyme Probe Technology
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基于结构的发现,一种新型的支架化合物作为与蛋白质结合的尿素毒素的结合竞争者

Ping Wang1,2, Shasha Liu1, Shengtian Zhao3

  • 1Institute of Medical Artificial Intelligence, Binzhou Medical University, Yantai, 264003, P.R., China.

Scientific reports
|November 15, 2024
PubMed
概括

新的候选药物在去除导致尿血的蛋白质结合尿素毒素 (PBUTs) 方面表现有前途. 这些化合物显示出比目前的透析方法更高的透析效率,为改善尿血症治疗提供了希望.

关键词:
具有约束力的竞争对手.在CKD中,它是最重要的.分子动力学模拟模型蛋白质结合的尿路性毒素虚拟选是一个虚拟的选.

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