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对乳腺癌患者认知障碍的风险预测模型的开发和验证

Xinmiao Zhang¹, Junyue Lu², Zhangyi Ding¹

¹School of Nursing, Jinzhou Medical University, Jinzhou, Liaoning, China.

|November 16, 2024

概括

认知障碍影响了19.62%的乳腺癌患者. 一种使用年龄和治疗等因素的新型诺莫格拉姆模型可以准确预测这种风险,从而改善了患者的护理.

科学领域:

在瘤学瘤学.
神经科学是一个神经科学.
医学统计医学统计

背景情况:

乳腺癌治疗经常导致认知障碍,严重影响患者的生活质量.
识别风险因素和开发预测工具对于管理这种并发症至关重要.

研究的目的:

确定乳腺癌患者认知障碍的危险因素.
开发和验证一个名ogram模型来预测这一群体的认知障碍.

主要方法:

分析了423名乳腺癌患者的方便样本.
通过LASSO和物流回归,确定了风险因素.
使用ROC曲线分析,校准曲线和决策曲线分析构建和验证了一个名ogram模型.

主要成果:

认知障碍的患病率为19.62%.
开发了一种包含年龄,教育,病理,治疗,情绪状态和疲劳等因素的命名图.
该模型实现了高预测准确性 (AUC培训:0.944,验证:0.931) 具有良好的校准和临床适用性.

结论:

开发的诺米图是预测乳腺癌患者认知障碍风险的可靠和直观工具.
该模型展示了强大的区别,校准和临床实用性.
这种工具可以帮助早期识别和管理认知障碍.

关键词:

乳腺癌是什么? 乳腺癌是什么?认知障碍认知障碍是一种认知障碍.这个名字叫做Nomogram.风险因素风险因素风险预测风险预测

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