在小儿甲状腺癌中基于成人的甲状腺成像报告和数据系统的诊断性能:一项回顾性研究
Wanying Li1, Yiyan Du1,2, Yao Wei1
1Department of Ultrasound, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
BMC medical imaging
|November 16, 2024
概括
儿童甲状腺结节携带更高的恶性瘤风险. 基于成人的超声波评估系统,ACR-TIRADS和C-TIRADS,在儿童中显示出强大的诊断性能,但仍然需要一个专门的系统.
科学领域:
- 放射学 放射学是一门学科.
- 儿科内分泌学 儿科内分泌学
- 在瘤学瘤学.
背景情况:
- 儿童甲状腺结节的恶性瘤风险比成年人高.
- 目前的超声波结节评估系统是为成年人设计的,缺乏儿科特异性.
- 在小儿甲状腺癌诊断中,评估现有的系统是非常必要的.
研究的目的:
- 评估美国放射学学院甲状腺成像报告和数据系统 (ACR-TIRADS) 和中国甲状腺成像报告和数据系统 (C-TIRADS) 在儿科甲状腺癌中的诊断性能.
- 为了比较基于成人的TIRADS系统在儿科患者群体中的有效性.
主要方法:
- 在136名接受手术或精细针吸收 (FNA) 的儿科患者 (≤18岁) 中,对177个甲状腺病变进行了回顾性审查.
- 分析了小儿甲状腺癌的超声波特征,并与良性结节进行了比较.
- 所有的结节都使用ACR-TIRADS和C-TIRADS进行了评估.
主要成果:
- 恶性儿科结节通常表现为固体组成 (94.8%),低可可性 (94.8-95.7%) 和微化 (78.3-84.3%).
- 无论是ACR-TIRADS还是C-TIRADS,都显示了儿童甲状腺癌的高诊断性能 (AUC 0.903-0.909).
- 对于这两种系统 (加权卡帕>0.90) 观察者之间有很强的一致性.
结论:
- 儿童甲状腺癌的ACR-TIRADS和C-TIRADS表现出卓越的诊断能力和观察者间可靠性.
- 尽管有效,但这些基于成人的系统强调了为儿科甲状腺结节提供专用超声波评估系统的需要.
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