胰腺透镜引导的胰腺管石:系统性审查和元分析
Peiyao Huang1, Hayat Khizar2, Wensong Song1
1Department of Gastroenterology, The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.
概括
在81%的患者中,胰腺扫描指导的石解术有效清除胰腺管道结石 (PDS). 这种内镜治疗证明了高临床成功率 (90%) 与低不良事件率 (12%),为慢性胰腺炎并发症提供了安全的选择.
科学领域:
- 胃肠病学和肝病学
- 内镜干预措施 内镜干预
- 胰腺疾病 胰腺疾病
背景情况:
- 胰腺管道结石 (PDS) 是慢性胰腺炎的一个重要并发症.
- PDS会引起严重的腹痛,使疾病恶化,增加胰腺癌的风险.
- 胰腺镜导向的光三是PDS的二线内镜治疗方法.
研究的目的:
- 评估胰腺扫描指导的 PDS 石治疗疗法的疗效和安全性.
- 为了确定完整的石头清除,临床成功和不良事件率.
- 为了比较电液压石化疗法与激光石化疗法的结果.
主要方法:
- 系统审查和对研究的元分析,截至2022年12月.
- 包括报告石头清除,临床成功和不良事件的研究.
- 在PubMed,Web of Science,Medline和Embase数据库中进行了搜索.
主要成果:
- 分析了17项涉及441名患者的研究.
- 聚合完整石头清除率: 81% (95% CI,0.74-0.88). 石头清除率: 81% (95% CI,0.74-0.88) 石头清除率: 81% (95% CI,0.74-0.88) 石头清除率: 81% (95% CI,0.74-0.88) 石头清除率: 81%
- 综合的临床成功率:90% (95% CI,0.84-0.95).
- 聚合的不良事件发生率:12% (95% CI,0.07-0.19).
结论:
- 胰腺镜导向的石是PDS的一种安全有效的治疗方法.
- 石头清除的高率和临床成功支持其使用.
- 不良事件的低发病率进一步验证了它的安全性.
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