相关实验视频

Updated: Jun 7, 2025

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
05:28

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

Published on: May 15, 2019

22.0K

颗粒物会通过系统性炎症和来自大脑的神经营养因子诱导类似抑郁的行为

Hui Li1, Xiaoyu Guo1, Pengxiang Li1

  • 1Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.

Environment international
|November 16, 2024
PubMed
概括

长期暴露于细颗粒物 (PM2.5) 污染可能会诱发小鼠的类似抑郁的行为. 这与大脑中的分子变化有关,特别是涉及MAPK/CREB/BDNF通路.

关键词:
行为行为行为.抑郁症 抑郁症 抑郁症电子生理学 电子生理学对于PM2.5来说,这是一个很好的例子.信号通道的信号通道.

更多相关视频

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

22.4K
Animal Models of Depression - Chronic Despair Model CDM05:47

Animal Models of Depression - Chronic Despair Model CDM

Published on: September 23, 2021

7.1K

相关概念视频

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
219
Stress and Mental Health01:30

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
77
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
51