在美国儿童医院的新生儿肠道手术后抗生素管理
Priyanka Jadhav1, Pamela M Choi2, Romeo Ignacio3
1University of California San Diego, School of Medicine, San Diego, CA, USA.
Journal of pediatric surgery
|November 16, 2024
概括
在新生儿肠道手术中,一天的术后抗生素足够,与较长时间相比,感染风险没有增加. 单一治疗Cefazolin也显示出较低的感染率.
科学领域:
- 新生儿手术 新生儿手术
- 儿科外科手术 儿科外科手术
- 传染病 传染病 传染病 传染病
背景情况:
- 有限的基于证据的指导方针存在于接受肠道手术的新生儿的外科手术期间使用抗生素.
- 目前的抗生素管理实践有很大的差异.
研究的目的:
- 评估接受肠道手术的新生儿的外科手术期间的抗生素给药实践.
- 根据抗生素策略,评估术后感染和其他结果的发生率.
主要方法:
- 使用儿科健康信息系统数据库 (2021) 进行的一项非干预性观察数据库研究.
- 确定的婴儿正在经历食道,十二指肠或节-节缩的修复.
- 分析了抗生素类型,持续时间和术后感染率 (细菌,真菌,抗生素耐药).
主要成果:
- 包括516名婴儿;39%接受了超过1天的抗生素.
- 在短期 (<1天) 和长期 (>1天) 抗生素治疗期间,术后感染率没有差异.
- 与其他疗法相比,单独治疗塞法林或塞福西的细菌感染率与其他疗法相似.
- 根据抗生素类型或持续时间,真菌感染率没有显著差异.
结论:
- 在新生儿肠道手术中,抗生素持续时间和类型存在很大差异.
- 一天的术后抗生素治疗与较低的感染发病率有关.
- 较长时间的抗生素治疗并没有降低感染风险;单独治疗塞法林的风险较低.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
2.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.5K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
82
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
82
Tonsillitis II: Management
103
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
103
Endocarditis IV: Nursing Management
2
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
2
Pneumonia IV: Management
299
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
299
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
102
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
102


