在面显微症中听力损失的患病率和风险因素
Danique van Dop1, Cornelia J J M Caron2, Lisa Nussbaum3
1Medical Student, Department of Oral and Maxillofacial Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
概括
听力障碍在面显微症 (CFM) 中非常普遍,通常与耳朵和下巴异常有关. 早期检测至关重要,因为即使没有明显的耳朵异常,听力损失也可能发生.
科学领域:
- 医学研究 医学研究
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 遗传学 是一个遗传学.
背景情况:
- 面显微症 (CFM) 经常涉及耳朵异常和听力障碍,但其确切的患病率和特征尚未完全理解.
- 这些异常与CFM患者的言语语言发育之间的关系需要进一步调查.
研究的目的:
- 确定诊断为面显微症 (CFM) 的患者的听力损伤相关的患病率和风险因素.
主要方法:
- 一项回顾性队列研究分析了213名CFM患者,通过听力测量来评估听力损伤.
- 预测变量包括裂口/口腔,CFM横向性和异常得分 (轨道,下,耳朵,神经,软组织,普鲁赞斯基-卡班).
- 使用后勤回归模型来分析预测因素与结果之间的关联.
主要成果:
- 在85.9%的CFM患者中检测到听力障碍,主要是导电性.
- 外耳异常与听力障碍有显著的相关性 (P < .001).
- 下 (M3) 和外耳 (E3) 异常的严重性得分与听力损失的存在和严重性相关 (P = .01,P < .001).
结论:
- 面异常的严重程度与CFM患者的听力损失患病率和严重程度相关.
- 临床医生必须对异侧或孤立的听力损失保持警,即使没有异侧面部或耳部异常.
- 尽管听力损失的患病率很高,但在这个群体中没有发现与语音语言发展有显著的关联.
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