核心脏病学的新视野:对外围动脉疾病的成像
Santiago Callegari1, Carlos Mena-Hurtado1, Kim G Smolderen2
1Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA; Vascular Medicine Outcomes Program, Yale University, New Haven, CT, USA.
新的成像技术显示出对诊断和评估外围动脉疾病 (PAD) 的前途. 射线追踪成像提供了大血管和微循环的全面视图,改善了患者风险分层和指导治疗.
科学领域:
- 心血管成像 - 心血管成像
- 放射化学 放射化学是指辐射化学.
- 血管医学 血管医学
背景情况:
- 下肢外周动脉疾病 (PAD) 涉及由于动脉狭窄和微血管疾病导致血液流动受损,导致显著的发病率和死亡率.
- 目前PAD的诊断工具在早期检测,风险分层和治疗评估方面缺乏准确性,主要关注阻塞性动脉样硬化疾病.
研究的目的:
- 综合审查外围动脉疾病 (PAD) 基于放射追踪器的成像.
- 突出PAD成像技术的进步,包括人工智能和大数据分析.
- 确定PAD研究和临床实践中放射性追踪成像的未来方向.
主要方法:
- 对PAD基于放射性追踪器成像的临床前和临床研究的综述.
- 在PAD中评估单光子发射计算机断层扫描 (SPECT) 和正子发射断层扫描 (PET) 成像.
- 讨论外周血管成像方面的挑战和新兴的分析方法.
主要成果:
- 包括SPECT和PET在内的放射追踪器成像在检测临床前和临床PAD中的 perfusion 变化方面表现得非常准确.
- 这些先进的成像模式有可能克服当前诊断方法的局限性.
- 透过射线追踪成像,可以获得有关 perfusion,代谢和分子过程的新鲜信息.
结论:
- 基于放射追踪器的成像具有显著的潜力,可以改善外周动脉疾病 (PAD) 的诊断,风险分层和治疗评估.
- 将人工智能和大数据分析与先进的成像技术相结合将对PAD管理的未来进展至关重要.
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