相关实验视频

Updated: Jun 7, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

[人类乳头瘤病毒和系统性红斑狼:一个系统性审查]

Tiphaine Goulenok¹, Karim Sacré²

¹Département de médecine interne, université Paris Cité, Hospital Bichat-Claude Bernard, AP-HP, Paris, France.

La Revue de medecine interne

|November 16, 2024

概括

人类乳头瘤病毒 (HPV) 疫苗接种和宫癌查对于预防HPV诱导的癌症至关重要,特别是在全身性狼 (SLE) 患者中. 然而,这些预防措施在SLE人群中未得到充分利用,这突显了严重的公共卫生差距.

科学领域:

在瘤学瘤学.
免疫学免疫学免疫学
公共卫生公共卫生

背景情况:

人类乳头瘤病毒 (HPV) 感染是各种癌症的主要原因,包括宫癌,门癌和口腔癌.
患有全身性红斑狼 (SLE) 的患者面临由于免疫抑制疗法而导致持续性HPV感染和随后的癌症的风险增加.
目前的HPV疫苗接种率和宫癌查率在患有SLE的成年人中低于最佳水平.

研究的目的:

突出改善系统性狼患者HPV预防策略的迫切需要.
为了强调HPV疫苗接种和查在这个脆弱人群中的低吸收率.
引入针对风险人群的针对HPV预防的创新方法.

主要方法:

关于HPV感染,癌症预防和系统性红斑狼的当前文献的综述.
对SLE患者接种疫苗和查指南的遵守情况的分析.
识别和评估新的预防策略,如追赶疫苗接种,治疗性疫苗接种和自我采样.

主要成果:

尽管疫苗有效,但在患有SLE的成年人中,HPV疫苗的覆盖率仍然很低.
宫癌查不一致地进行,只有一半的狼患者遵守建议.
创新的策略,如阴道自取样和追赶HPV疫苗接种,有望改善高风险群体的预防.

结论:

在系统性狼患者中,针对HPV诱导的癌症的预防措施实施不充分.
提高医疗保健提供者和患者对HPV疫苗接种的认识至关重要.
有针对性的干预措施是必要的,以改善HPV预防和减少SLE患者的癌症风险.

关键词:

宫癌是因为宫癌.癌症查癌症查宫癌是发生在宫癌的原因之一.这是一个Dépistage.这是一个HPVHPVHPV.感染HPV病毒的感染.狼是一种狼.系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.疫苗接种疫苗接种

更多相关视频

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Published on: March 8, 2012

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line

Published on: September 28, 2022

相关概念视频

Genome-wide Association Studies-GWAS

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

Mechanisms of Retrovirus-induced Cancers

Mechanisms of Retrovirus-induced Cancers

Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...