内压力是否会根据外腔室排水而变化? 一个现实世界的临床观察研究
Dohee Kwon1, Lindsay Riskey1, Abdulkadir Kamal1
1Department of Nursing, University of Texas Southwestern Medical Center, Dallas, TX, USA.
概括
外腔室排水 (EVDs) 在脑脊液 (CSF) 排水后暂时降低内压力 (ICP). 然而,ICP的变化仍然存在,这凸显了对标准化EVD管理和ICP监测实践的需要.
科学领域:
- 神经外科 神经外科
- 关键护理医学 关键护理医学
- 神经学 神经学
背景情况:
- 外腔室排水管 (EVDs) 对于通过转移脑脊液 (CSF) 来控制增加的内压力 (ICP) 是至关重要的.
- 目前的EVD管理和ICP记录实践缺乏标准化和强有力的证据.
- 在机构和从业人员对EVD管理的方法中存在显著的差异.
研究的目的:
- 在CSF排水之前和之后,调查患有EVD的患者的ICP波动.
- 量化CSF排水对ICP水平的直接影响.
- 在EVD管理过程中识别ICP测量的变化.
主要方法:
- 一项现实世界的观察性研究,涉及30名患有EVD的成年患者.
- 在10分钟的紧,1分钟的排水和随后的10分钟的紧期间记录了ICP.
- 从226个独立的排水塞事件中收集的数据,跨越了每个患者的多个观察期.
主要成果:
- 一分钟的脑脊液排水导致了统计学上显著的平均ICP下降1.1mmHg (p <0.05).
- 埃博拉病毒病的最常见迹象是占据大量病变的病变.
- 观察到的ICP变异范围很广,在患者检查中没有发现一致的临床变化.
结论:
- 脊髓液排水可以暂时减少ICP.
- CSF排水对ICP的影响是短暂的.
- 进一步的研究是必不可少的,以建立基于证据的指导方针,以安全管理埃博拉病毒和ICP监测.
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