在互联网游戏障碍中灰色物质不对称的变化
Shuaiyu Chen1,2, Jin Yan1,2, Matthew Lock1,2
1Center for Cognition and Brain Disorders, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang Province, China.
Scientific reports
|November 16, 2024
概括
患有互联网游戏障碍 (IGD) 的人表现出大脑灰质不对称的变化,特别是在与动机和注意力相关的区域. 这些结构上的差异可以准确地区分IGD患者和健康用户.
科学领域:
- 神经成像是一种神经成像.
- 神经科学是一个神经科学.
- 大脑的不对称性
背景情况:
- 结构不对称性是一个关键的大脑属性,在各种疾病中发生变化.
- 在互联网游戏障碍 (IGD) 中大脑不对称的变化尚未得到充分理解.
研究的目的:
- 调查互联网游戏障碍 (IGD) 患者的灰质不对称性.
- 为了确定潜在的神经成像生物标志物用于病态游戏依赖.
主要方法:
- 收集了来自104名IGD患者和104名娱乐游戏用户 (RGU) 的高分辨率结构MRI数据.
- 应用全脑基于声素的不对称性 (VBA) 方法来检测灰色物质异常.
- 使用支向量机 (SVM) 根据不对称的特征对IGD进行分类.
主要成果:
- 患有IGD的个体在包括中枢前额叶皮质 (mPFC),轨道前额叶皮质,前额叶皮质和形/形回旋在内的区域表现出不对称的灰质变化.
- 这些区域涉及到动机,自我反思,信息整合和视觉空间注意力.
- 非典型的不对称特征准确地区分了IGD主题与RGUs.
结论:
- 动机奖励,视觉空间和默认模式电路中破坏的结构不对称性可能作为识别病态游戏依赖的生物标志物.
- 这些发现有助于更好地理解IGD的结构基础.
- 提供了开发强迫性游戏干预措施的见解.
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