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Updated: Jun 7, 2025

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设计,合成和生物评价的新型pleuromutilin衍生品与甲基西林耐药的金黄色葡萄球菌 - 向醇链接组

Yunpeng Yi1, Jiaming Zhang2, Shuqian Lin1

  • 1Shandong Provincial Engineering Research Center for Animal Health Products, Institute of Poultry Science, Shandong Academy of Agricultural Science, Jinan, 250100, Shandong, China.

European journal of medicinal chemistry
|November 17, 2024
PubMed
概括

新的pleuromutilin衍生物显示出对抗抗甲素耐药黄金葡萄球菌 (MRSA) 的强有力的活性. 化合物a4表现出快速杀菌作用和降低耐药性,为MRSA感染提供了一个有希望的治疗候选者.

关键词:
具有抗菌活性,具有抗菌活性.在MRSA中,MRSA可能是MRSA.分子对接是分子对接.型素的衍生品 型素的衍生品

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