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使用营养预后指数进行营养风险评估,预测晚期慢性肝病患者的死亡率

Ketsia Meneses Souza Santos¹, Ramona Souza da Silva Baqueiro Boulhosa², Laís Spindola Garcêz³

¹Food, Nutrition and Health Post-Graduation Program, Federal University of Bahia, Salvador, Bahia, Brazil.

Nutrition (Burbank, Los Angeles County, Calif.)

|November 17, 2024

概括

营养预后指数 (NPI) 可以确定晚期慢性肝病 (ACLD) 患者的营养风险. 在ACLD患者中,NPI截止值<41预测12个月内高死亡风险.

科学领域:

肝病学肝病学是一种肝病学.
临床营养学临床营养学
预测预测预测预测预测

背景情况:

慢性肝病 (CLD) 的早期临床预后和死亡率降低仍然是重大挑战.
营养预后指数 (NPI) 对CLD患者营养评估的有用性尚未完全理解.

研究的目的:

建立一个NPI切割值来识别晚期CLD (ACLD) 患者的营养风险.
评估NPI对ACLD相关死亡率的预测能力.

主要方法:

一项前性队列研究,涉及120名住院的ACLD患者.
使用NPI和皇家免费医院营养优先级工具 (RFH-NPT) 评估营养不良风险.
通过ROC曲线确定NPI切线;通过费舍尔精确测试和卡帕指数评估关联;使用PearsonChi-square测试检查死亡相关性.

主要成果:

一个NPI截止值<41确定了82.5%的患者具有营养风险.
NPI显示了与RFH-NPT (Kappa=0.34) 的统计学上显著的关联.
患有NPI<41的患者在12个月内死亡率为82.1%.

结论:

国家营养指标是一个有价值,简单和有效的工具,用于识别营养风险并帮助ACLD的早期预后.
需要在不同的CLD群体中进一步验证NPI.

关键词:

晚期慢性肝病晚期慢性肝病营养预测指数营养预测指数营养评估营养评估营养风险营养风险营养查营养查

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