肠道和肠道营养时间在eICU合作研究数据库种族:一个回顾性观察性研究
An-Kwok Ian Wong1, Paul E Wischmeyer2, Haesung Lee3
1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina; Division of Translational Biomedical Informatics, Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina.
The Journal of surgical research
|November 17, 2024
概括
在为重症监护室 (ICU) 患者提供早期营养的时间上没有发现种族差异. 相反,性别,疾病严重程度和医院特征等因素影响了营养启动. 建议使用当前数据进行进一步的研究.
科学领域:
- 关键护理医学 关键护理医学
- 营养支持 营养支持
- 健康差距 研究 研究 研究 研究
背景情况:
- 在营养不良方面确立了种族和民族差异.
- 在重症监护室 (ICU) 提供早期营养与改善患者的治疗结果有关.
- 对于ICU患者的早期营养供应存在种族差异,目前尚不清楚.
研究的目的:
- 调查ICU患者的肠道营养 (EN) 和肠外营养 (PN) 开始的时间.
- 检查在提供早期营养方面潜在的种族差异.
- 确定影响营养递送时间的因素.
主要方法:
- 从2014-2015年开始对eICU-协作研究数据库 (eICU-CRD) 的分析.
- 在208家医院中包括符合EN和PN条件的患者.
- 利用考克斯的比例危险模型来评估比赛和营养开始时间之间的关联,调整为共变量.
主要成果:
- 没有发现种族与EN或PN开始的时间之间有显著的关联.
- 性别,顺序性器官衰竭评估 (SOFA) 评分,体重指数和医院特征等因素与营养供应的变化有关.
- 在黑白患者中,EN启动的中位时间为1.5天,PN启动的中位时间为7.4天.
结论:
- 在研究的ICU人群中,种族差异没有被确定为EN和PN交付时间的重要因素.
- 性别,体重指数,疾病严重程度 (SOFA分数) 和医院特定因素似乎在确定营养递送时间方面更有影响力.
- 需要利用更现代的数据进行进一步的研究来证实这些发现.
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