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Updated: Jun 7, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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参与Sigma-1R抑制的M2R的结构决定因素

Chang Liu1, I-Shan Chen2, Muruj Barri3

  • 1Division of Biophysics and Neurobiology, Department of Molecular and Cellular Physiology, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan; Program of Physiological Sciences, Field of Life Science, Department of Advanced Studies, SOKENDAI (The Graduate University for Advanced Studies), Hayama, Japan.

The Journal of biological chemistry
|November 17, 2024
PubMed
概括

西格玛-1受体 (S1R) 与M2-肌糖性乙胆受体 (M2R) 相互作用,降低其细胞表面表达和功能. 这种相互作用对于调节M2R信号来说至关重要,特别是在像ALS这样的神经疾病中.

关键词:
M2 - 肌肉酸乙胆受体抑制抑制抑制的抑制作用补丁灯 - 补丁灯 - 补丁灯西格玛-1受体是什么?结构决定因素 结构决定因素

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