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Updated: Jun 7, 2025

Preparation of Synaptic Plasma Membrane and Postsynaptic Density Proteins Using a Discontinuous Sucrose Gradient
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Hsc70系统保持突触SNARE蛋白SNAP-25在组装能力的状态,并延迟其聚合

Karishma Bhasne1, Antonia Bogoian-Mullen1, Eugenia M Clerico1

  • 1Department of Biochemistry & Molecular Biology, University of Massachusetts, Amherst Massachusetts, USA.

The Journal of biological chemistry
|November 17, 2024
PubMed
概括

热冲击蛋白70 (Hsp70) 和它的协伴蛋白CSPα阻止了SNAP-25的聚合,这是神经递质释放中的关键蛋白质. 这种陪伴活动确保SNAP-25保持为SNARE复合体形成做好准备,这对突触功能至关重要.

关键词:
这就是CSPα.在Hsp70中,Hsp70是Hsp70.在SNAP-25中使用.这里是SNARE综合体.陪伴者是一个陪伴者.神经传递的神经传递蛋白质聚合蛋白质的聚合物

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