肺部不规则性:一种新的超声波标志物用于初级Sjögren病中的肺部参与
Francesco Ferro1, Gaetano La Rocca1, Elena Elefante1
1Rheumatology Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Via Roma 67, 56126 Pisa, Italy.
Joint bone spine
|November 17, 2024
概括
肺超声波 (LUS) 上的多叶膜异常可以有效地选初级Sjögren患者的间歇性肺病 (ILD).
科学领域:
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
背景情况:
- 连接组织疾病,包括原发性肖格伦病 (SjD),与间歇性肺病 (ILD) 有关.
- 肺部超声波 (LUS) 是评估ILD的拟议工具,但其在SjD中的实用性,特别是关于肺部不规则 (PI) 的实用性,尚未研究.
研究的目的:
- 调查肺部超声波 (LUS) 上的肺部不规则 (PI) 的作用,以评估初级斯乔格伦病 (SjD) 中的肺部参与.
- 确定LUS上的PI是否可以帮助在SjD患者中查和诊断ILD.
主要方法:
- 招募了一组患有或没有已知的肺部感染的原发性斯乔格伦病 (SjD) 患者,他们接受了胸部CT扫描.
- 进行了肺部超声波 (LUS),并分配了总和部分肺部不规则性 (PI) 评分.
- 患者根据CT扫描结果进行分类:正常,非SjD肺部异常,SjD相关的非ILD肺部异常,已确定的ILD和新诊断的ILD.
主要成果:
- 在42名没有已知肺部疾病的患者中,CT检测发现了4例新的ILD病例.
- 与正常CT扫描或非ILD异常患者相比,已确诊或新诊断的ILD患者的总和后期较低PI得分显著更高.
- 低位后期PI得分显示ILD的诊断准确性 (AUC) 比总PI得分更高,截止值为15,产生86.6%的灵敏度和84.2%的特异性.
- PI得分与HRCT沃里克得分有很强的相关性,并且与肺功能测试 (PFT) 的相关性比HRCT发现更高.
结论:
- 肺超声波 (LUS) 上的肺部不规则 (PI) 是一个有希望的工具,用于评估初级Sjögren病 (SjD) 中的肺部参与.
- PI评估,特别是侧重于后下肺领域,对于查SjD患者间歇性肺病 (ILD) 似乎是有效的.
- 这种专注的PI评估可能可以在临床实践中节省时间,同时保持诊断准确性.
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