多发性硬化症患者的尿道炎:系统性审查和元分析
Saeed Vaheb1, Mohammad Yazdan Panah2, Vahid Shaygannejad3
1Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Survey of ophthalmology
|November 17, 2024
概括
患有多发性硬化症 (MS) 的人群中毛囊炎的总体患病率为1.1%. 中间性脑膜炎是最常见的类型,影响0.6%的MS患者. 专家的早期诊断至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经系统疾病.
- 患有多发性硬化症 (pwMS) 的人经常经历眼部并发症.
- 尿道炎是与MS相关的明显的眼部并发症.
研究的目的:
- 为了确定pwMS.pwMS中脑膜炎的总体患病率.
- 为了确定不同类型的脑膜炎在pwMS中的流行率.
- 通过元分析,综合现有关于MS相关脑膜炎的研究.
主要方法:
- 在PubMed/MEDLINE,Scopus,EMBASE和Web of Science (1990-2023) 中进行系统的文献搜索.
- 使用R软件对12项涉及54,402名pwMS的研究进行了元分析.
- 随机效应模型用于计算聚合流行率和95%置信区间.
主要成果:
- 在pwMS中,毛囊炎的综合流行率为1.1% (95% CI:0.6-1.7%).
- 中间性脑膜炎是最常见的类型,患病率为0.6% (95% CI:0.2-1.0%).
- 在研究中观察到显著的异质性 (I2 > 87%,p < 0.01).
结论:
- 尿道炎影响大约1.1%的MS患者.
- 中间性脑膜炎是这个人群中最常见的亚型.
- 在pwMS中迅速诊断和专业治疗脑膜炎至关重要.
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