在EDIA纵向婴儿队列中,食纤维和肠道微生物组组成之间的关联
Marianne K Lalli1, Tuuli Ei Salo2, Leena Hakola3
1Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
The American journal of clinical nutrition
|November 17, 2024
概括
在断奶期间引入补充性食纤维有助于婴儿肠道微生物群的多样化. 麦等食物中的特定纤维促进有益的细菌和代谢物,对婴儿的长期健康至关重要.
科学领域:
- 微生物组研究的研究.
- 婴儿营养 婴儿营养
- 代谢学 代谢学 代谢学
背景情况:
- 婴儿的肠道微生物组在第一年迅速发展,影响健康.
- 饮食是一个关键因素,但补充性食物纤维的作用尚不清楚.
研究的目的:
- 研究补充食品中的食纤维如何塑造婴儿肠道微生物组的发展.
- 探索纤维摄入量,细菌物种和代谢物之间的关联.
主要方法:
- 婴儿肠道微生物组 (N=68) 和代谢组 (N=33) 的纵向和横截面分析.
- 三天的食物记录评估了3,6,9和12个月的纤维摄入量.
- 通过metagenomics识别的细菌种群;使用LC-MS分析的代谢物.
主要成果:
- 在补充性食物纤维和细菌物种之间发现了176个关联.
- 植物纤维最初模仿了母乳养的微生物群,并与特定的代谢物联系在一起.
- 麦纤维与*Faecalibacterium prausnitzii*密切相关,表明微生物组的成熟.
结论:
- 补充的食纤维在断奶期间促进肠道微生物群的多样化和稳定性.
- 早期和特定的纤维引入显著影响微生物的组成和功能.
- 饮食建议应优先考虑纤维,以支持婴儿肠道健康.
关键词:
母乳养 哺乳期 母乳养补充养 补充养 补充养饮食纤维的食物纤维.便代谢物质的代谢物质我们的肠道微生物组.人类母乳是人类的母乳.人类牛奶中的寡糖类.婴儿 婴儿 婴儿 婴儿 婴儿转基因组学是指转基因组学.断奶 断奶 断奶 断奶 断奶更多相关视频
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