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Updated: Jun 7, 2025

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
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Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

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在瘤透的Treg中,YAP通过在硬基质上升调Lars2来增强线粒体OXPHOS

Jingchao Bai1,2,3, Meinan Yan1,2,3, Yihan Xu1,2,3

  • 1Department of Gastrointestinal Cancer Biology, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.

Journal for immunotherapy of cancer
|November 17, 2024
PubMed
概括

瘤透调节T细胞 (TI-Tregs) 通过通过YAP增加线粒体OXPHOS来适应瘤微环境. 缺乏YAP或低素饮食会损害TI-Treg功能,提供一种新的瘤治疗策略.

关键词:
细胞外矩阵 细胞外矩阵线粒体中的线粒体.固体瘤是一个固体瘤.一个T调节单元 - Treg调节单元

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