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吗啡治疗限制了在口腔状细胞癌症中对免疫治疗的反应

Lisa A McIlvried1, Andre A Martel Matos1, Mona M Yuan1

  • 1Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Journal for immunotherapy of cancer
|November 17, 2024
PubMed
概括

像吗啡这样的阿片类药物抑制抗瘤免疫力,并通过作用于T细胞来降低癌症免疫疗法的有效性. 用特定的抗剂阻断mu阿片类受体 (OPRM1) 可以防止这种免疫抑制并恢复治疗疗效.

关键词:
头部和部癌症 头部和部癌症免疫检查点抑制剂 免疫检查点抑制剂免疫抑制是一种免疫抑制.一个T细胞细胞.

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