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心脏移植后的皮肤癌:系统性审查

Nathalia Hoffmann Guarda Aguzzoli¹, Ana Laura Bueno¹, Yağmur Halezeroğlu²

¹Dermatology Department, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.

Anais brasileiros de dermatologia

|November 17, 2024

概括

皮肤癌是心脏移植接受者的一个重大问题,报告的非黑色素瘤皮肤癌,状细胞癌,基底细胞癌和恶性黑色素瘤的发病率各不相同. 皮肤科医生对于管理这些患者的皮肤癌风险至关重要.

科学领域:

在瘤学瘤学.
皮肤病学皮肤病学
移植医学移植医学移植医学

背景情况:

皮肤癌是心脏移植后最常见的恶性瘤.
免疫抑制疗法增加了移植接受者的癌症风险.
皮肤学监测对于心脏移植患者至关重要.

研究的目的:

系统地审查心脏移植接受者皮肤癌的发生情况.
分析该人口中各种皮肤癌类型的发病率.

主要方法:

关于EMBASE和PubMed数据库的系统文献综述 (2021年8月至9月).
包括对心脏移植患者的回顾性和前性队列研究.
排除不对器官类型或皮肤癌频率进行分层的研究.

主要成果:

包括来自20个国家的37项研究 (1974-2015年).
非黑色素瘤皮肤癌发生率:0.97%-52.8%.
状细胞癌: 1.19%-89%; 基底细胞癌: 2%-63%; 恶性黑色素瘤: 0.94%-4.6%.

结论:

皮肤癌在心脏移植接受者中是一个重大的流行病学挑战.
方法上的异质性被注意到,但研究结果强调了皮肤病护理的重要性.
加强皮肤科医生在心脏移植患者的长期随访中的关键作用.

关键词:

心脏移植心脏移植手术免疫抑制疗法是一种免疫抑制疗法.皮肤新生体的形成.

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