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Updated: Jun 7, 2025

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在SAM的C-2处探索化酶基质耐受性

Phillip T Lowe1, Isabeau Lüddecke1, David O'Hagan1

  • 1School of Chemistry and Biomedical Sciences Research Centre, University of St Andrews, North Haugh, KY16 9ST, St Andrews, UK.

Chembiochem : a European journal of chemical biology
|November 17, 2024
PubMed
概括

用修改的S-adenosyl-L-methionine (SAM) 基质探索了化酶活性. 发现了某些替代剂的新活动,为其在用于医学成像的-18放射标记中的使用提供了信息.

关键词:
生物催化剂的生物催化剂氨酸酶是一种化酶.基板的范围范围范围.

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Bromination and chlorination of aromatic rings by electrophilic aromatic substitution reactions are easily achieved, but fluorination and iodination are difficult to achieve. Fluorine is so reactive that its reaction with benzene is difficult to control, resulting in poor yields of monofluoroaromatic products. To address this, Selectfluor reagent is used as a fluorine source in which a fluorine atom is bonded to a positively charged nitrogen.
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