扩散权重磁共振成像 (DW-MRI) 在甲状腺结节的分化中的有效性
Bilgen Mehpare Özer1, Yüksel Pabuşçu2, Serdar Tarhan2
1Department of Radiology, Sincan Training and Research Hospital, Gökçek, 250. Cadde 2/A Sincan, Ankara, Turkey. bilgenmehpare.ozer@saglik.gov.tr.
Thyroid research
|November 17, 2024
概括
扩散权重磁共振成像 (DW-MRI) 有效地区分良性和恶性甲状腺结节. 在b500和b800的较低明显扩散系数 (ADC) 值表明恶性病,有助于在没有对比剂的情况下进行诊断.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 甲状腺结节很常见,区分良性和恶性类型对于患者管理至关重要.
- 扩散加权磁共振成像 (DW-MRI) 提供了一种非侵入性方法来表征甲状腺病变.
研究的目的:
- 为了比较两种不同的b值 (b500s/mm2和b800s/mm2) 在扩散权重磁共振成像 (DW-MRI) 中的有效性,以区分良性和恶性甲状腺结节.
- 为了评估来自DW-MRI的不同b值的显微扩散系数 (ADC) 值的诊断性能.
主要方法:
- 对26名手术前诊断为结节性或多结节性的患者的部MRI检查的回顾性分析.
- 测量显微扩散系数 (ADC) 值在DW-MRI上在b 500秒/mm2和b 800秒/mm2的 46 个甲状腺结节.
- 将DW-MRI检测结果与组织病理学结果进行比较,以确定诊断准确度.
主要成果:
- 组织病理学分析发现了37个良性和9个恶性结节.
- 与良性结节相比,恶性结节的平均ADC值在b500 (1259.65 ± 328.13与19037.48 ± 472.74) 和b800 (1081.72 ± 200.23与1610.44 ± 418.06) 两种情况下都显著低于良性结节.
- 在1.1 × 10−3的截止值下,b 500的ADC值显示出83.3%的灵敏度和90.0%的特异性,而b 800的ADC值显示出71.4%的灵敏度和89.7%的特异性,用于区分恶性和良性病理.
结论:
- 扩散权重磁共振成像 (DW-MRI) 是区分良性和恶性甲状腺结节的一个有价值的工具.
- 在此研究中,在b 500 s/mm2获得的ADC值与b 800 s/mm2相比显示出稍高的灵敏度.
- 在不需要对比剂的情况下,DW-MRI提供了有效的甲状腺结节特征.
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