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Updated: Jun 7, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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在肺腺癌中,ADAMTS16在TGF-β1激活时通过反循环驱动上皮质-介质细胞过渡和转移

Lingyan Xiao1, Qian Li2, Shuaijun Chen3

  • 1Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Cell death & disease
|November 17, 2024
PubMed
概括

ADAMTS16通过激活TGF-β信号传递和上皮细胞-介质细胞过渡 (EMT) 来促进肺腺癌 (LUAD) 转移. 针对ADAMTS16或TGF-β1/SOX4轴可能会抑制LUAD的进展.

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