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COVID-19 流行病及其对肌肉发育不良症类型1患者的影响:我们学到的教训
Vera E A Kleinveld1, Johanna E Bruijnes2, Samuel Labrecque1
1Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
肌肉性缩症1型 (DM1) 患者的COVID-19患病率较低,但住院率较高. 流行病管理策略没有影响DM1疾病的发展过程,这表明它们可以重复使用.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 肌性缩症1型 (DM1) 患者有心肺症状,增加严重的COVID-19风险.
- COVID-19大流行对DM1患者的影响需要对管理策略进行调查.
研究的目的:
- 评估COVID-19大流行对DM1患者的影响.
- 在流行病期间为DM1患者的管理策略提供信息.
主要方法:
- 在MYODRAFT数据库中从195名DM1患者中获取了COVID-19感染数据.
- 对82名患者/代理人进行了关于COVID-19症状,福祉和护理的问卷调查.
- 将流行病数据与流行病前数据进行比较.
主要成果:
- 在DM1患者中,COVID-19的患病率 (9.2%) 低于荷兰人口 (11.5%).
- 在DM1患者 (22.2%) 中,COVID-19的住院率高于一般人口 (3.6%).
- 两名DM1患者死于COVID-19;取消的预约经常发生. 患者报告的身体功能保持稳定,但代理人注意到幸福感下降.
结论:
- 尽管感染率相似,但DM1患者面临严重COVID-19结局的更高风险.
- 流行病管理策略没有对DM1疾病进展产生负面影响.
- 现有策略可以在类似的未来公共卫生危机中重新应用.
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