超高血压患者的泛免疫炎症值和肉症之间的关联,NHANES 1999-2018年
Lu Long1,2, Bingquan Xiong1, Zhidan Luo2
1Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Journal of clinical hypertension (Greenwich, Conn.)
|November 18, 2024
概括
高泛免疫炎症值 (PIV) 在高血压患者中显著增加了肉症风险. 糖尿病进一步放大了这种风险,强调了早期PIV查和管理的必要性.
科学领域:
- 老年学是指老年学的学科.
- 心脏病学 心脏病学
- 免疫学 免疫学 免疫学
背景情况:
- 皮症对高血压患者的预后产生负面影响,导致并发症.
- 早期发现和干预萨科佩尼亚对于改善这一群体的结果至关重要.
研究的目的:
- 在高血压患者中调查泛免疫炎症值 (PIV) 和肉症之间的关联.
- 为了确定PIV作为一种潜在的肉类的风险因素,并探索其与糖尿病的相互作用.
主要方法:
- 使用NHANES数据 (1999-2018) 来自9253名高血压患者的横截面研究.
- 使用了逻辑和线性回归,限制立方线 (RCS) 和子组分析.
- 根据PIV水平,患者被分为四分之一.
主要成果:
- 与最低四分位数相比,最高PIV四分位数显示了36%的肉类的风险增加 (OR=1.36,95% CI:1.04-1.77).
- RCS分析表明,PIV水平上升与肉症风险之间存在线性关系.
- 糖尿病在患有高PIV的患者中协同增加了肉症风险 (相互作用的p=0.007).
结论:
- 升高的PIV是高血压个体中肉症的独立风险因素.
- 糖尿病加剧了高PIV的背景下,缩症的风险.
- 监测PIV水平对于管理高血压患者,特别是糖尿病患者的萨尔科佩尼亚风险很重要.
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