在退化的化CoreValve/Evolut爆炸剂中使用SAPIEN 3门的Redo-TAVI
David Meier1,2, Anish Nigade3, Althea Lai4
1Department of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
概括
在大多数情况下,在退化的CoreValve/Evolut (CV/EV) 中,使用SAPIEN 3 (S3) 植入红通管大动脉植入 (TAVI) 显示出令人满意的水力动力性能. 需要进一步的研究来了解S3不扩张和突起的长期影响.
科学领域:
- 心血管医学 心血管医学
- 生物医学工程 生物医学工程
- 干预心脏病学 干预心脏病学
背景情况:
- 重新通透导管大动脉植入 (TAVI) 对于失败的生物假体非常重要.
- 在退化的CoreValve/Evolut (CV/EV) 中,SAPIEN 3 (S3) 适用于重复TAVI,但其性能尚未完全理解.
研究的目的:
- 评估S3的水力动力学功能在植入到已扩展的,化的CV/EV跨导管大动脉 (TAV) 后.
- 评估 CV/EV 门病理对 redo-TAVI 结果的影响.
主要方法:
- 使用ISO 5840-3标准对4个S3 TAV植入化CV/EV探头进行了ex vivo水力动力测试.
- 血液动力学参数的评估,包括平均梯度 (MG),有效孔面积 (EOA),反分数 (RF) 和传单运动.
主要成果:
- 在化的CV/EV门中S3植入减少了MG和峰值速度.
- 在大多数S3植入物中观察到足够的EOA和可接受的RF (<20%).
- 观察到S3框架的不扩张和小册子的旋转,突出影响S3小册子.
结论:
- 在化CV/EV门中S3植入显示出一般令人满意的水力动力性能.
- 观察到稳定的传单溢出,但S3不扩张和突起的长期影响需要进一步调查.
相关概念视频
Aortic Regurgitation I: Introduction
3
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
3
Mitral Regurgitation III: Medical Management
4
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
4
Heart Valves
4.3K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
4.3K
Mitral Valve Prolapse I: Introduction
4
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
4
Mitral Valve Prolapse II: Assessment and Management
3
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
3
Mitral Stenosis I: Introduction
2
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
2


