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一种跨学科的方法提供了关于化合物42对DPP9的明显选择性的见解

Olivier Beyens1, Sam Corthaut2, Anne-Marie Lambeir2

  • 1Laboratory of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium.

ChemMedChem
|November 18, 2024
PubMed
概括

研究人员确定了二乙酶9 (DPP9) 中的一个关键差异,它允许选择性抑制二乙酶8 (DPP8). 这一发现有助于开发针对涉及这些蛋白酶的疾病的向疗法.

关键词:
DPP8 DPP8 DPP8 DPP8 DPP8 DPP8 DPP8 DPP8 DPP8 DPP8 DPP8DPP9 DPP9 DPP9 DPP9 DPP9 DPP9 DPP9 DPP9 DPP9抑制剂是一种抑制剂.分子动力学分子动力学萨克斯 (SAXS) 的时间.

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