相关实验视频

Updated: Jun 7, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

系统性硬化和非常早期系统性硬化 (VEDOSS) 患者的维生素D血清水平

Giovanna Cuomo¹, Maria Consiglia Trotta², Giovanbattista D'Amico³

¹Department of Precision Medicine, "Luigi Vanvitelli" University of Campania, Naples, Italy.

Journal of scleroderma and related disorders

|November 18, 2024

概括

系统性硬化症患者的维生素D水平比早期的患者低. 较低的维生素D与系统性硬化症中更严重的皮肤和血管问题有关.

科学领域:

免疫学免疫学免疫学
内分泌学在内分泌学.
类风湿病学类风湿病学

背景情况:

维生素D具有免疫调节作用.
系统性硬化症 (SSc) 涉及复杂的病理生理路径.
研究维生素D在SSc进展中的作用至关重要.

研究的目的:

为了比较SSc患者和非常早期SSc (vE-SSc) 患者之间的维生素D水平.
探索维生素D水平与SSc和vE-SSc中的临床/生化参数之间的相关性.

主要方法:

一项病例控制研究包括126名参与者 (80名SSc,46名VE-SSc).
收集的数据包括人类学,临床,生化和仪器参数.
测量血清维生素D水平,并与其他变量相关联.

主要成果:

与vE-SSc患者相比,SSc患者的维生素D水平明显较低.
在SSc患者中,较低的维生素D水平与增加的皮肤和血管参与有关.
在vE-SSc中,只有自身抗体配置文件与维生素D水平相关.

结论:

维生素D缺乏症在SSc患者中很普遍,但在VE-SSc患者中通常充足.
低维他命症D与SSc的晚期皮肤和微血管疾病有关.
对补充维生素D来预防SSc进展的进一步研究是有必要的.

关键词:

系统性硬化症系统性硬化症维多斯的视频非常早期的系统性硬化症.维生素D是维生素D的重要组成部分.

更多相关视频

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

相关概念视频

Role of Skin in Vitamin D Synthesis

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...