影响血管瘤患者预后的风险因素分析:一项回顾性研究
Yezhou Li1, Leilei Tian2, Dajun Sun1
1Department of Vascular Surgery, China-Japan Union Hospital of Jilin University Changchun 130033, Jilin, China.
American journal of cancer research
|November 18, 2024
概括
这项研究确定了血管瘤生存的关键预后因素,包括系统性免疫炎症指数 (SII),初级瘤部位,转移和化疗. 一个经过验证的诺姆图有助于预测患者的生存结果.
科学领域:
- 在瘤学瘤学.
- 医学统计 医学统计
背景情况:
- 血管肉瘤是一种罕见且具有攻击性的软组织肉瘤,预后不佳.
- 确定可靠的预后因素对于改善患者管理和生存结果至关重要.
研究的目的:
- 为了确定血管肉瘤患者生存的独立预后因素.
- 开发和验证用于血管瘤存活的预测性名录模型.
主要方法:
- 对105名血管肉瘤患者的回顾性分析,对50名患者进行外部验证.
- 评估临床数据,周围血液指标 (WBC,PLT,LYM,ALB,PLR,SII,PIN) 和治疗方式.
- 多变量考克斯回归和名图构造用于生存预测.
主要成果:
- 系统性免疫炎症指数 (SII),主要瘤部位,转移和化疗被确定为独立的预后因素.
- 开发的名图表显示出高准确性 (AUC 0.803-0.837) 和稳定性在预测1,3年和5年生存率.
- 在SII和主要瘤部位/化疗之间观察到显著的相互作用.
结论:
- SII,主要瘤部位,转移和化疗对于预测血管肉瘤预后至关重要.
- 经过验证的诺米图像作为一个可靠的工具,用于在血管瘤患者个性化生存预测.
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