在患有阻塞性睡眠呼吸暂停综合征的患者中对眼睛表面进行评估
Reza Ghaffari1, Hamed Ghassemi1, Khosro Sadeghniiat Haghighi2
1Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Journal of current ophthalmology
|November 18, 2024
概括
阻塞性睡眠呼吸暂停 (OSA) 患者的眼破裂时间 (TBUT) 减少,这表明眼睛干燥的风险更高. 然而,梅博米腺功能障碍 (MGD) 和结节的患病率在OSA患者中仍然相似.
科学领域:
- 眼科医生 眼科 眼科
- 睡眠医学 睡眠医学
- 眼睛表面疾病 眼睛表面疾病
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种影响全身健康的常见疾病.
- 眼睛表面疾病,包括眼睛干燥,梅博米腺功能障碍 (MGD) 和结合性沙拉症,在患有OSA的患者中越来越多地被认可.
- 了解这些疾病在OSA患者中的患病率对于全面的患者护理至关重要.
研究的目的:
- 评估在被诊断患有OSA的患者中干眼,MGD和结眼的患病率.
- 为了比较OSA患者和对照组之间的眼表面参数.
主要方法:
- 包括37名OSA患者和31名健康对照.
- 进行了全面的眼科检查和眼睛表面评估.
- 用于MGD评估的meibography和前段光学连贯性断层扫描用于撕裂半月体高度测量.
主要成果:
- 与对照组 (11.47 ± 4.52,P < 0.001) 相比,OSA组的平均撕裂分解时间 (TBUT) 显着较低 (8.17 ± 3.70).
- 在OSA和对照组之间,梅博米腺表达,堵塞,眼边缘疏通,梅博斯科尔,撕裂半月板高度和结合性拉症分级得分相似.
- 两组之间在MGD或结合性病的流行率上没有发现显著差异.
结论:
- 患有OSA的患者表现出减少的TBUT,这表明对干眼的敏感性增加.
- 尽管TBUT降低了,但MGD和结节的患病率与对照组相比,在OSA患者中并没有显著增加.
- 进一步的研究可能会探索将OSA与干眼症状联系在一起的特定机制,并调查有针对性的干眼干预措施.
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