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Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

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Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
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Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
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亚特拉斯:一个大型阵列,芯片内计算的SPAD摄像头,用于多光扩散相关性光谱学.

Alistair Gorman1, Neil Finlayson1, Ahmet T Erdogan1

  • 1Institute for Integrated Micro and Nano Systems, School of Engineering, University of Edinburgh, Edinburgh, UK.

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概括
此摘要是机器生成的。

亚特拉斯传感器可以实时进行芯片上的计算,用于单光子相关谱. 这项技术适用于组织动态的in-vivo扩散相关谱 (DCS) 测量.

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科学领域:

  • 光子学是指光子学的使用方法.
  • 生物医学工程 生物医学工程
  • 集成电路 集成电路

背景情况:

  • 单光子雪崩二极管 (SPAD) 阵列对于光学传感至关重要.
  • 扩散相关谱学 (DCS) 需要有效计算自相关函数.
  • 现有的DCS方法可能是计算密集型,缺乏实时处理能力.

研究的目的:

  • 介绍ATLAS,一个具有嵌入式自相对应计算的新型512x512 SPAD数组.
  • 为了实现实时的芯片处理,用于单光子相关性光谱应用.
  • 为了证明ATLAS适用于in-vivo扩散相关谱 (DCS) 测量的适用性.

主要方法:

  • 使用3D堆叠CMOS技术实现512x512 SPAD阵列.
  • 开发一个共享的每宏像素SRAM架构,用于并行自相对应计算.
  • 使用最小的自相对应滞后时间为1μs,以获得高时间分辨率.

主要成果:

  • 在芯片上直接计算自相关函数的演示.
  • 在实时的身体组织中成功解决脱节关系时间变化.
  • 实现了长的源探测器分离,与用于大脑血流监测的领先光学模式相提并论.

结论:

  • 亚特拉斯传感器促进了实时,芯片上的DCS测量.
  • 该系统已被验证用于体内测量,包括袖口闭塞和额头心脏信号.
  • 亚特拉斯显示了促进组织动态和血流的非侵入性监测的巨大潜力.