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相关概念视频

Electrospray Ionization (ESI) Mass Spectrometry01:12

Electrospray Ionization (ESI) Mass Spectrometry

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Higher molecular weight biomolecules are nonvolatile compounds that may decompose before ionizing or vaporizing during mass analysis with conventional electron impact ionization methods. Accordingly, electrospray ionization (ESI) is the favored method for vaporizing and ionizing biomolecules as it circumvents rapid fragmentation and enables the recording of mass signals for the entire biomolecule.
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
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Mass Spectrometers01:16

Mass Spectrometers

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This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
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Atomic Emission Spectroscopy: Instrumentation01:22

Atomic Emission Spectroscopy: Instrumentation

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The instrumentation of atomic emission spectrometry (AES) involves various components, including atomization devices that convert samples into gas-phase atoms and ions. There are two main types of atomization devices: continuous and discrete atomizers.  Continuous atomizers, like plasmas and flames, introduce samples in a constant stream, while discrete atomizers inject individual samples using syringes or autosamplers. The most common discrete atomizer is the electrothermal atomizer.
341
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

572
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
572
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

649
In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
649
Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

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Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and signal-to-noise ratio for the analyte. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.
Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called collision-induced...
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相关实验视频

Updated: Jun 7, 2025

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
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Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

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一个开源的孤立数据采集与触发脉冲生成的离子移动性光谱仪.

Tim Kobelt1, Martin Lippmann1, Alexander Nitschke1

  • 1Leibniz University Hannover, Institute of Electrical Engineering and Measurement Technology, Department of Sensors and Measurement Technology, Appelstr. 9A, 30167 Hannover, Germany.

HardwareX
|November 18, 2024
PubMed
概括

我们为先进的离子移动性光谱仪 (IMS) 和其他仪器开发了开源数据采集硬件. 这种硬件可以同步测量,并为复杂的分析应用提供灵活的并行数字化.

关键词:
数据采集 数据采集离子移动性光谱仪离子移动性光谱仪光学隔离的光学隔离.脉冲发生的脉冲生成.

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Measurement of Ultrafast Vibrational Coherences in Polyatomic Radical Cations with Strong-Field Adiabatic Ionization
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Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry
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Measurement of Ultrafast Vibrational Coherences in Polyatomic Radical Cations with Strong-Field Adiabatic Ionization
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Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry
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科学领域:

  • 分析化学 分析化学
  • 仪器化 仪器化 仪器化
  • 开源硬件 开源硬件

背景情况:

  • 离子移动性光谱仪 (IMS) 对于微量气体检测和医学和食品质量等分析应用至关重要.
  • 将IMS与其他设备连接起来,需要同步的电子设备.
  • 在IMS中,仪器的复杂性正在增加.

研究的目的:

  • 介绍一个开源数据采集硬件解决方案.
  • 为了满足先进的IMS和其他分析仪器的需求.
  • 为了实现同步操作和灵活的数据采集.

主要方法:

  • 开发了开源数据采集硬件.
  • 集成触发器脉冲生成用于同步.
  • 集成的双,隔离的16位模拟数字转换器 (ADC) 采样率为250kS/s.
  • 实现了电隔离的触发器输入.

主要成果:

  • 硬件为IMS离子门和外部设备的同步操作提供触发脉冲.
  • 通过使用两个以高达250kS/s的隔离ADC实现并行数字化.
  • 电隔离确保了同步启动,这对于与气相色谱仪等仪器的合至关重要.
  • 孤立的ADC为仪器设置的地面潜力定义提供了灵活性.

结论:

  • 展示的开源硬件有效地解决了先进的IMS中的同步和数据采集挑战.
  • 它提供了一种灵活而强大的解决方案,适用于各种分析仪器设置.
  • 这一发展促进了更复杂和同步的分析工作流.